Reactivity: | Human |
Applications: | FC |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal Antibody |
Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
Gene Name: | CUB domain containing protein 1 |
Gene Symbol: | CDCP1 |
Synonyms: | CD318; TRASK; SIMA135 |
Gene ID: | 64866 |
UniProt ID: | Q9H5V8 |
Clone ID: | 5M1R5 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-666 of human CDCP1 (NP_073753.3). |
Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
Purification Method: | Affinity purification |
Concentration: | 0.04 mg/mL |
Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-CDCP1 antibody |
Background
This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of this gene.
Images
![]() | Flow cytometry: 1×10^6 HEL cells (negative control,left) and PC-3 cells (right) were surface-stained with ABflo® 647 Rabbit anti-Human CDCP1 mAb (A22499,2 μg/mL,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,2 μg/mL,blue line). Non-fluorescently stained cells was used as blank control (red line). |
![]() | Flow cytometry: 1×10^6 PC-3 cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Human CDCP1 mAb (A22499,5 μl/Test,right). |
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