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ABflo® 647 Rabbit anti-Human Integrin alpha 3/CD49c mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
| Gene Name: | integrin subunit alpha 3 |
| Gene Symbol: | ITGA3 |
| Synonyms: | JEB7; VL3A; CD49C; FRP-2; GAPB3; ILNEB; MSK18; VCA-2; VLA3a; GAP-B3 |
| Gene ID: | 3675 |
| UniProt ID: | P26006 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 466-620 of human Integrin alpha 3/CD49c (NP_002195.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-ITGA3 Antibody |
Background
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis.
Images
 | Flow cytometry: 1×10^6 K-562 cells (negative control,left) and A-431 cells (right) were surface-stained with ABflo® 647 Rabbit anti-Human Integrin alpha 3/CD49c mAb (A26581,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 A-431 cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Human Integrin alpha 3/CD49c mAb (A26581,5 μl/Test,right). |
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