Reactivity: | Human |
Applications: | IF/ICC, FC (intra) |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal Antibody |
Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
Gene Name: | Lysosomal associated membrane protein 2 |
Gene Symbol: | LAMP2 |
Synonyms: | DND; LAMPB; CD107b; LAMP-2; LGP-96; LGP110 |
Gene ID: | 3920 |
UniProt ID: | P13473 |
Clone ID: | 8I3Q5 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-375 of human LAMP2 (NP_002285.1). |
Dilution: | IF/ICC,1:50 - 1:200|FC (intra),5 μl per 10^6 cells in 100 μl volume |
Purification Method: | Affinity purification |
Concentration: | 0.04 mg/mL |
Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-LAMP2 Antibody |
Background
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins.
Images
![]() | Confocal imaging of HeLa cells using ABflo® 647 Rabbit anti-Human LAMP2 mAb (A22217, dilution 1:200). DAPI was used for nuclear staining (Blue). Objective: 100x. |
![]() | Flow cytometry:1×10^6 knockout (KO) HeLa cells (negative control,left) and HeLa cells (right) were intracellularly-stained with ABflo® 647 Rabbit anti-Human LAMP2 mAb(A22217,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
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