Your shopping cart is empty!
ABflo® 647 Rabbit anti-Human/Mouse Integrin alpha 5 (ITGA5/CD49e) mAb (100 T)
| Reactivity: | Human,Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
| Gene Name: | Integrin subunit alpha 5 |
| Gene Symbol: | ITGA5 |
| Synonyms: | FNRA; CD49e; VLA-5; VLA5A |
| Gene ID: | 3678 |
| UniProt ID: | P08648 |
| Clone ID: | 2G2E8 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 42-995 of human Integrin alpha 5 (ITGA5/CD49e)(NP_002196.4) |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-ITGA5 Antibody |
Background
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
Images
 | Flow cytometry:1×10^6 SH-SY5Y cells (negative control,Left) and U-87MG cells (Right) were surface-stained with ABflo® 647 Rabbit anti-Human/Mouse Integrin alpha 5 (ITGA5/CD49e) mAb (A22772,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 NIH/3T3 cells were surface-stained with ABflo® 647 Rabbit anti- Human/Mouse Integrin alpha 5 (ITGA5/CD49e) mAb(A22772,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line).Non-fluorescently stained NIH/3T3 cells was used as blank control (red line). |
 | Flow cytometry:1×10^6 U-87MG cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti- Human/Mouse Integrin alpha 5 (ITGA5/CD49e) mAb(A22772,5 μl/Test,right). |
 | Flow cytometry:1×10^6 NIH/3T3 cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti- Human/Mouse Integrin alpha 5 (ITGA5/CD49e) mAb(A22772,5 μl/Test,right). |
 | Flow cytometry:1×10^6 Human PBMC were surface-stained with ABflo® 647 Rabbit anti-Human Integrin alpha 5 (ITGA5/CD49e) mAb(A22772,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
You may also be interested in:
Related Products
-10%
-16%
