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ABflo® 647 Rabbit anti-Mouse IL-33R/ST2 mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
| Gene Name: | interleukin 1 receptor-like 1 |
| Gene Symbol: | Il1rl1 |
| Synonyms: | T1; St2; DER4; Ly84; ST2L; Fit-1; T1/ST2; St2-rs1 |
| Gene ID: | 17082 |
| UniProt ID: | P14719 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-332 of mouse IL-33R /ST2 (NP_001020773.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Il1rl1 antibody |
Background
Enables interleukin-33 binding activity and interleukin-33 receptor activity. Involved in several processes, including negative regulation of T-helper 1 type immune response; positive regulation of macrophage activation; and regulation of cytokine production. Acts upstream of or within negative regulation of I-kappaB kinase/NF-kappaB signaling. Located in external side of plasma membrane and extracellular matrix. Is expressed in several structures, including immune system; musculoskeletal system; salivary gland; skin; and visual system. Human ortholog(s) of this gene implicated in asthma and coronary artery disease. Orthologous to human IL1RL1 (interleukin 1 receptor like 1).
Images
 | Flow cytometry: 1×10^6 P815 cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Mouse IL-33R/ST2 mAb (A26401,5 μl/Test,right). |
 | Flow cytometry: 1×10^6 C2C12 cells (negative control,left) and P815 cells (right) were surface-stained with ABflo® 647 Rabbit anti-Mouse IL-33R/ST2 mAb (A26401,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
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