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ABflo® 647 Rabbit anti-Rat CD31 mAb (100 T)
| Reactivity: | Rat |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
| Gene Name: | platelet and endothelial cell adhesion molecule 1 |
| Gene Symbol: | Pecam1 |
| Synonyms: | CD31; Pecam |
| Gene ID: | 29583 |
| UniProt ID: | Q3SWT0 |
| Clone ID: | 1P9N5 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-585 of rat CD31 (NP_113779.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.01 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Pecam1 antibody |
Background
Enables protein phosphatase binding activity. Involved in several processes, including cellular response to interferon-gamma; negative regulation of GTPase activity; and negative regulation of actin filament polymerization. Located in cell surface and ruffle. Used to study pulmonary hypertension. Biomarker of bacterial pneumonia; orchitis; and osteoarthritis. Human ortholog(s) of this gene implicated in coronary artery disease (multiple); lung non-small cell carcinoma; neuroblastoma; and psoriatic arthritis. Orthologous to human PECAM1 (platelet and endothelial cell adhesion molecule 1).
Images
 | Flow cytometry: 1×10^6 PC-12 cells (negative control,left) and Rat Splenocytes (right) were surface-stained with ABflo® 647 Rabbit anti-Rat CD31 mAb (A25153,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 Rat Splenocytes were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Rat CD31 mAb (A25153,5 μl/Test,right). |
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