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Reactivity: | Human |
Applications: | FC |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal Antibody |
Conjugation: | ABflo® 700. Ex:690nm. Em:713nm. |
Gene Name: | platelet and endothelial cell adhesion molecule 1 |
Gene Symbol: | PECAM1 |
Synonyms: | CD31; PECA1; GPIIA'; PECAM-1; endoCAM; CD31/EndoCAM |
Gene ID: | 5175 |
UniProt ID: | P16284 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-601 of human CD31/PECAM1 (NP_000433.4). |
Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
Purification Method: | Affinity purification |
Concentration: | 0.02 mg/ml |
Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-PECAM1 Antibody |
Background
The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.
Images
![]() | Flow cytometry: 1×10^6 SK-BR-3 cells (negative control,left) and HEL cells (right) were surface-stained with ABflo® 700 Rabbit anti-Human CD31/PECAM1 mAb (A26238,5 μl/Test,orange line) or ABflo® 700 Rabbit IgG isotype control (A25976,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
![]() | Flow cytometry: 1×10^6 HEL cells were surface-stained with ABflo® 700 Rabbit IgG isotype control (A25976,5 μl/Test,left) or ABflo® 700 Rabbit anti-Human CD31/PECAM1 mAb (A26238,5 μl/Test,right). |
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