Reactivity: | Human |
Applications: | FC |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal Antibody |
Conjugation: | APC. Ex:650nm. Em:660nm. |
Gene Name: | natural cytotoxicity triggering receptor 1 |
Gene Symbol: | NCR1 |
Synonyms: | LY94; CD335; NKP46; NK-p46 |
Gene ID: | 9437 |
UniProt ID: | O76036 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-254 of human CD335/NKp46 (NP_004820.2). |
Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
Purification Method: | Affinity purification |
Concentration: | 0.01 mg/ml |
Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-NCR1 Antibody |
Background
Predicted to be involved in cellular defense response; regulation of natural killer cell mediated cytotoxicity; and signal transduction. Predicted to act upstream of or within defense response to virus and detection of virus. Predicted to be located in cell surface. Predicted to be part of SWI/SNF complex. Predicted to be active in plasma membrane. Biomarker of acquired immunodeficiency syndrome; anogenital venereal wart; hepatitis C; and lymphoproliferative syndrome.
Images
![]() | Flow cytometry: 1×10^6 293T cells (negative control,left) and 293T (Transfection,right) cells were surface-stained with APC Rabbit anti-Human CD335/NKp46 mAb (A26606,5 μl/Test,orange line) or APC Rabbit IgG isotype control (A24173,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
![]() | Flow cytometry: 1×10^6 293T (Transfection) cells were surface-stained with APC Rabbit IgG isotype control (A24173,5 μl/Test,left) or APC Rabbit anti-Human CD335/NKp46 mAb (A26606,5 μl/Test,right). |
![]() | Flow cytometry:1×10^6 Human PBMC were surface-stained with ABflo® 450 Mouse anti-Human CD56 mAb (5 μl/Test) and APC Rabbit IgG isotype control (A24173,5 μl/Test,left) or APC Rabbit anti-Human CD335/NKp46 mAb (A26606,5 μl/Test,right).Cells in the lymphocytes gate were used for analysis. |
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