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| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rat |
| Isotype: | IgG2a, kappa |
| Clonality: | Monoclonal Antibody |
| Conjugation: | FITC. Ex:491nm. Em:516nm. |
| Gene Name: | CD19 antigen |
| Gene Symbol: | Cd19 |
| Synonyms: | N/A |
| Gene ID: | 12478 |
| Clone ID: | 2Q0K4 |
| Immunogen: | Recombinant protein of Mouse CD19. |
| Dilution: | FC,The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system. |
| Purification Method: | Affinity purification |
| Concentration: | 0.50 mg/ml |
| Buffer: | 10 mM NaH₂PO₄, 150 mM NaCl, 0.09% NaN₃,0.1% gelatin, pH7.2 |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Cd19 Antibody |
Background
Involved in several processes, including B-1 B cell differentiation; positive regulation of phosphatidylinositol 3-kinase activity; and positive regulation of release of sequestered calcium ion into cytosol. Acts upstream of or within B cell receptor signaling pathway. Located in external side of plasma membrane. Is integral component of plasma membrane. Is expressed in liver and spleen. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human CD19 (CD19 molecule).
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