Reactivity: | Human |
Applications: | FC |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal Antibody |
Conjugation: | PE. Ex:565nm. Em:574nm. |
Gene Name: | TNF receptor superfamily member 14 |
Gene Symbol: | TNFRSF14 |
Synonyms: | TR2; ATAR; HVEA; HVEM; CD270; LIGHTR |
Gene ID: | 8764 |
UniProt ID: | Q92956 |
Clone ID: | 9R7I2 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 39-162 of human CD270/HVEM(NP_003811.2) |
Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
Purification Method: | Affinity purification |
Concentration: | 0.04 mg/mL |
Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-TNFRSF14 Antibody |
Background
This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants.
Images
![]() | Flow cytometry: 1×10^6 HAP1 cells (negative control,left) and HEL cells (right) were surface-stained with PE Rabbit anti-Human CD270/HVEM mAb (A25414,5 μl/Test,orange line) or PE Rabbit IgG isotype control (A24172,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
![]() | Flow cytometry: 1×10^6 HEL cells were surface-stained with PE Rabbit IgG isotype control (A24172,5 μl/Test,left) or PE Rabbit anti-Human CD270/HVEM mAb (A25414,5 μl/Test,right). |
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