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| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | PE. Ex:565nm. Em:574nm. |
| Gene Name: | inducible T cell costimulator |
| Gene Symbol: | ICOS |
| Synonyms: | AILIM; CD278; CVID1 |
| Gene ID: | 29851 |
| UniProt ID: | Q9Y6W8 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to aminoacids 21-141 of human ICOS/CD278 (NP_036224.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.02 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-ICOS antibody |
Background
The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.
Images
![]() | Flow cytometry: 1×10^6 293F cells (negative control,left) and MOLT-4 cells (right) were surface-stained with PE Rabbit anti-Human ICOS/CD278 mAb (A26444,5 μl/Test,orange line) or PE Rabbit IgG isotype control (A24172,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
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