PE Rabbit anti-Human Integrin alpha 3/CD49c mAb (100 T)

Brand: Abclonal
Cat. #: A26580
Availability: In Stock

$408.00

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Description

Reactivity:	Human
Applications:	FC
Host Species:	Rabbit
Isotype:	IgG
Clonality:	Monoclonal Antibody
Conjugation:	PE. Ex:565nm. Em:574nm.
Gene Name:	integrin subunit alpha 3
Gene Symbol:	ITGA3
Synonyms:	JEB7; VL3A; CD49C; FRP-2; GAPB3; ILNEB; MSK18; VCA-2; VLA3a; GAP-B3
Gene ID:	3675
UniProt ID:	P26006
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 466-620 of human Integrin alpha 3/CD49c (NP_002195.1).
Dilution:	FC,5 μl per 10^6 cells in 100 μl volume
Purification Method:	Affinity purification
Concentration:	0.04 mg/ml
Buffer:	PBS with 0.09% Sodium azide,0.2% BSA, pH7.3.
Storage:	Store at -20°C. Avoid freeze / thaw cycles.
Documents:	Manual-ITGA3 Antibody

Background

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis.

Images

	Flow cytometry: 1×10^6 K-562 cells (negative control,left) and A-431 cells (right) were surface-stained with PE Rabbit anti-Human Integrin alpha 3/CD49c mAb (A26580,5 μl/Test,orange line) or PE Rabbit IgG isotype control (A24172,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
	Flow cytometry: 1×10^6 A-431 cells were surface-stained with PE Rabbit IgG isotype control (A24172,5 μl/Test,left) or PE Rabbit anti-Human Integrin alpha 3/CD49c mAb (A26580,5 μl/Test,right).