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| Reactivity: | Mouse |
| Applications: | FC (intra) |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | PE. Ex:565nm. Em:574nm. |
| Gene Name: | CD68 antigen |
| Gene Symbol: | Cd68 |
| Synonyms: | Lamp4; gp110; Scard1 |
| Gene ID: | 12514 |
| UniProt ID: | P31996 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-291 of mouse CD68 (NP_001277987.1). |
| Dilution: | FC (intra),5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Cd68 antibody |
Background
Involved in several processes, including cellular response to lipopolysaccharide; cellular response to oxidised low-density lipoprotein particle stimulus; and negative regulation of dendritic cell antigen processing and presentation. Acts upstream of or within aging and cellular response to organic substance. Located in lysosome and plasma membrane. Is expressed in several structures, including central nervous system; embryo mesenchyme; heart blood vessel; liver; and spleen. Orthologous to human CD68 (CD68 molecule).
Images
 | Flow cytometry: 1×10^6 NIH/3T3 cells (Low Expression,left) and RAW 264.7 cells (right) were intracellularly-stained with PE Rabbit anti-Mouse CD68 mAb (A26390,5 μl/Test,orange line) or PE Rabbit IgG isotype control (A24172,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 RAW 264.7 cells were intracellularly-stained with PE Rabbit IgG isotype control (A24172,5 μl/Test,left) or PE Rabbit anti-Mouse CD68 mAb (A26390,5 μl/Test,right). |
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