Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | HLA-DOA rabbit polyclonal antibody |
Gene Name: | HLA class II histocompatibility antigen, DO alpha chain |
Synonyms: | MHC DN-alpha, MHC DZ alpha, MHC class II antigen DOA, HLA-DOA, HLA-DNA, HLA-DZA, DO alpha chain precursor, HLADZ, Lymphocyte antigen, HLA DNA, HLA D0 alpha |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human HLA-DOA |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 28kDa |
Observed MW. | 35kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1500 | Raji, Jurkat |
Background
HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.
Images
![]() | Western blot analysis of HLADOA (GB113229) at dilution of 1: 1500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |