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| Reactivity: | Human, Mouse, Rat |
| Applications: | WB |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal antibody |
| Gene Name: | ectonucleoside triphosphate diphosphohydrolase 5 (inactive) |
| Gene Symbol: | GDF3 |
| Synonyms: | PCPH; CD39L4; NTPDase-5 |
| Gene ID: | 957 |
| UniProt ID: | Q9NR23 |
| Clone ID: | 24GB6110 |
| Immunogen: | A synthesized peptide derived from human GDF3 |
| Dilution: | WB 1:1,000-1:5,000 |
| Purification Method: | Affinity purified |
| Concentration: | Lot dependent |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Background
The protein ENTPD5 encoded by this gene is similar to E-type nucleotidases (NTPases)/ecto-ATPase/apyrases. NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD5 contains 4 apyrase-conserved regions which is characteristic of NTPases.
Images
 | Western blotting analysis using anti-growth differentiation factor 3 antibody (Cat#61186). Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-growth differentiation factor 3 antibody (Cat#61186, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using NaQ™ ECL Substrate Kit (Cat#716). |
 | Western blotting analysis using anti-growth differentiation factor 3 antibody (Cat#61186). Growth differentiation factor 3 expression in wild type (WT) and growth differentiation factor 3 (GDF3) shRNA knockdown (KD) HeLa cells with 20 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with anti-growth differentiation factor 3 antibody (Cat#61186, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using NaQ™ ECL Substrate Kit (Cat#716). |
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