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| Reactivity: | Human |
| Applications: | WB |
| Host Species: | Mouse |
| Isotype: | IgG2a |
| Clonality: | Monoclonal antibody |
| Gene Name: | glyoxylate and hydroxypyruvate reductase |
| Gene Symbol: | GRHPR |
| Synonyms: | PH2; GLXR; GLYD |
| Gene ID: | 9380 |
| UniProt ID: | Q9UBQ7 |
| Clone ID: | 24GB6270 |
| Immunogen: | Recombinant protein of human GRHPR |
| Dilution: | WB 1:2,500-1:5,000 |
| Purification Method: | Affinity purified |
| Concentration: | Lot dependent |
| Buffer: | PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Background
This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene.
Images
 | Western blotting analysis using anti-GRHPR antibody (Cat#63508). Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-GRHPR antibody (Cat#63508, 1:5,000) and HRP-conjugated goat anti-mouse secondary antibody (Cat#101, 1:20,000) respectively. Image was developed using FeQ™ ECL Substrate Kit (Cat#226). |
 | Western blotting analysis using anti-GRHPR antibody (Cat#63508). GRHPR expression in wild type (WT) and GRHPR shRNA knockdown (KD) HeLa cells with 20 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with anti-GRHPR antibody (Cat#63508, 1:5,000) and HRP-conjugated goat anti-mouse secondary antibody (Cat#101, 1:20,000) respectively. Image was developed using anti-FeQ™ ECL Substrate Kit (Cat#226). |
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