Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | NSUN2/SAKI rabbit polyclonal antibody |
Gene Name: | RNA cytosine C(5)-methyltransferase NSUN2 |
Synonyms: | Myc-induced SUN domain-containing protein, Misu, NOL1/NOP2/Sun domain family member 2, Nsun2, mRNA cytosine C(5)-methyltransferase, tRNA cytosine C(5)-methyltransferase |
Immunogen: | Recombinant protein corresponding to Mouse NSUN2/SAKI |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 85 kDa |
Observed MW. | 85 kDa |
Uniprot ID: | Q1HFZ0 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | liver, heart |
Background
RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. Methylates cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. Not able to modify tRNAs at positions 48 or 49. May act downstream of Myc to regulate epidermal cell growth and proliferation.
Images
![]() | Western blot analysis of NSUN2 (GB112498) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |