| Reactivity: | M,R & R |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PACT (PKR activating protein) / PRKRA rabbit polyclonal |
Gene Name: | Interferon-inducible double-stranded RNA-dependent protein kinase activator A |
Synonyms: | DYT16, HSD 14, HSD14, PACT, PKR associated protein X, PKR associating protein X, PRKRA, RAX |
Immunogen: | Recombinant protein corresponding to Mouse PRKRA |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 34 kDa |
Observed MW. | 34 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1500 | brain, testis, heart |
IHC | Rat | 1: 600-1: 1200 | brain, cerebellum, substantia nigra, frontal lobe |
Background
This gene encodes a protein kinase activated by double-stranded RNA which mediates the effects of interferon in response to viral infection. Mutations in this gene have been associated with dystonia. Alternative splicing results in multiple transcript variants.
Images
| Western blot analysis of PRKRA (GB113542) at dilution of 1: 1500 |
| Immunohistochemistry analysis of paraffin-embedded rat brain using PRKRA (GB113542) at dilution of 1: 1200 |
| Immunohistochemistry analysis of paraffin-embedded rat cerebellum using PRKRA (GB113542) at dilution of 1: 1200 |
| Immunohistochemistry analysis of paraffin-embedded rat frontal lobe using PRKRA (GB113542) at dilution of 1: 1200 |
| Immunohistochemistry analysis of paraffin-embedded rat substantia nigra using PRKRA (GB113542) at dilution of 1: 1200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |