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ABflo® 488 Rabbit anti-Human CD200/OX2 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | CD200 molecule |
| Gene Symbol: | CD200 |
| Synonyms: | MRC; MOX1; MOX2; OX-2 |
| Gene ID: | 4345 |
| UniProt ID: | P41217 |
| Clone ID: | 6B9F9 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 31-232 of human CD200/OX2 (NP_001352780.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.01 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-CD200 Antibody |
Background
This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms.
Images
 | Flow cytometry: 1×10^6 Jurkat cells(negative control,left) and SK-MEL-28 cells (right) were surface-stained with ABflo® 488 Rabbit anti-Human CD200/OX2 mAb(A23741,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line).Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 SK-MEL-28 cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human CD200/OX2 mAb(A23741,5 μl/Test,right). |
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