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| Reactivity: | Human, Mouse, Rat |
| Applications: | WB, ELISA |
| Host Species: | Rabbit |
| Clonality: | Polyclonal antibody |
| Gene Name: | DDB1 and CUL4 associated factor 11 |
| Gene Symbol: | DCAF11 |
| Synonyms: | GL014; WDR23; PRO2389; DCAF11 |
| Gene ID: | 80344 |
| UniProt ID: | Q8TEB1 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human DCAF11 (NP_079506.3). |
| Dilution: | WB 1:1000-1:5000 |
| Purification Method: | Affinity purification |
| Concentration: | 2.63 mg/mL |
| Buffer: | Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-DCAF11 antibody |
Background
This gene encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. Multiple alternatively spliced transcript variants have been found for this gene.
Images
 | Western blot analysis of lysates from Mouse liver, using DCAF11 Rabbit pAb (A15519) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 20s. |
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