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| Reactivity: | Human |
| Applications: | WB, ELISA |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Polyclonal antibody |
| Gene Name: | fem-1 homolog B |
| Gene Symbol: | FEM1B |
| Synonyms: | F1AA; F1A-ALPHA; FEM1-beta; FEM1B |
| Gene ID: | 10116 |
| UniProt ID: | Q9UK73 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 368-627 of human FEM1B (NP_056137.1). |
| Dilution: | WB 1:500-1:1000 |
| Purification Method: | Affinity purification |
| Concentration: | 1.56 mg/ml |
| Buffer: | PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-FEM1B antibody |
Background
This gene encodes an ankyrin repeat protein that belongs to the death receptor-associated family of proteins and plays a role in mediating apoptosis. The encoded protein is also thought to function in the replication stress-induced checkpoint signaling pathway via interaction with checkpoint kinase 1.
Images
 | Western blot analysis of lysates from A-549 cells, using FEM1B Rabbit pAb (A12802) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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