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| Reactivity: | Human, Mouse, Rat |
| Applications: | WB, IF/IC, ELISA |
| Host Species: | Rabbit |
| Clonality: | Polyclonal antibody |
| Gene Name: | late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 |
| Gene Symbol: | LAMTOR1 |
| Synonyms: | p18; PDRO; C11orf59; p27RF-Rho; Ragulator1; LAMTOR1 |
| Gene ID: | 55004 |
| UniProt ID: | Q6IAA8 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-161 of human LAMTOR1 (NP_060377.1). |
| Dilution: | WB 1:500-1:1000; IF/IC 1:50-1:100 |
| Purification Method: | Affinity purification |
| Concentration: | 3.09 mg/ml |
| Buffer: | PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-LAMTOR1 antibody |
Background
Enables GTPase binding activity. Contributes to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Involved in several processes, including cholesterol homeostasis; positive regulation of TOR signaling; and regulation of cholesterol transport. Located in lysosome. Part of Ragulator complex.
Images
 | Immunofluorescence analysis of C6 cells using LAMTOR1 Rabbit pAb (A11619) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of NIH-3T3 cells using LAMTOR1 Rabbit pAb (A11619) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of U-2 OS cells using LAMTOR1 Rabbit pAb (A11619) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution. Blue: DAPI for nuclear staining. |
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