Reactivity: | Human, Mouse, Rat |
Applications: | WB, ELISA |
Host Species: | Rabbit |
Clonality: | Polyclonal antibody |
Gene Name: | methylthioribose-1-phosphate isomerase 1 |
Gene Symbol: | MRI1 |
Synonyms: | M1Pi; MRDI; MTNA; Ypr118w; MRI1 |
Gene ID: | 84245 |
UniProt ID: | Q9BV20 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-369 of human MRI1 (NP_001026897.1). |
Dilution: | WB 1:500-1:2000 |
Purification Method: | Affinity purification |
Concentration: | 5.22 mg/ml |
Buffer: | PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Documents: | Manual-MRI1 antibody |
Background
This enzyme functions in the methionine salvage pathway by catalyzing the interconversion of methylthioribose-1-phosphate and methythioribulose-1-phosphate. Elevated expression of the encoded protein is associated with metastatic melanoma and this protein promotes melanoma cell invasion independent of its enzymatic activity. Mutations in this gene may be associated with vanishing white matter disease (VMWD).
Images
![]() | Western blot analysis of various lysates using MRI1 Rabbit pAb (A14344) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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