Reactivity: | H,M,R & M,R |
Applications: | WB & IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | MSY2/YBOX2/YBX2 rabbit polyclonal |
Gene Name: | Y-box-binding protein 2 |
Synonyms: | CONTRIN, CSDA3, DBPC, DNA binding protein C, MSY2, MSY2 homolog, Y box binding protein 2, YBX2 |
Immunogen: | Recombinant protein corresponding to Mouse MSY2/YBOX2/YBX2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 38 kDa |
Observed MW. | 55 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | testis, lung |
IHC | Mouse, Rat | 1: 1800-1: 3600 | testis |
Background
MSY2 and YB-2 (MSY3,4) belong to the Y-box family of multifunctional proteins that regulate both transcription and translation (1–3). Y-box proteins interact with a wide variety of nucleic acid structures to act as transcription factors and mRNA masking proteins (1). The modular structure of Y-box proteins includes a highly conserved N-terminal cold-shock domain (CSD, equivalent to the bacterial cold-shock proteins) and four basic C-terminal domains containing arginine clusters and aromatic residues (4). MSY2 is expressed in testis and ovary where it may repress translation of parental mRNA (5,6).
Images
![]() | Western blot analysis of Ybx2 (GB113143) at dilution of 1: 2000 |
![]() | Immunohistochemistry analysis of paraffin-embedded mouse testis using Ybx2 (GB113143) at dilution of 1: 3600 |
Immunohistochemistry analysis of paraffin-embedded rat testis using Ybx2 (GB113143) at dilution of 1: 3600 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |