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Recombinant Anti-Mast cell tryptase Mouse mAb (100 μl)
| Reactivity: | H,M |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Tryptase alpha/beta-1 |
Synonyms: | MCP7, TPS1, TPS2, TPSAB1, TPSB1, Tryptase 1, tryptase alpha/beta 1, Tryptase beta 1, Tryptase I |
Immunogen: | Recombinant protein corresponding to Human Mast cell tryptase |
Uniprot ID: | Q15661 |
Isotype: | IgG1 |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Predicted MW. / Observed MW. | 31 kDa / 31 kDa |
Product Usage Information
IHC/IF | Human, Mouse | 1: 500-1: 1000 | colon, skin |
Background
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates.
Images
| Immunohistochemistry analysis of paraffin embedded human colon using Mast cell tryptase (GB15109) at dilution of 1: 100 |
| Immunohistochemistry analysis of paraffin embedded mouse skin using Mast cell tryptase (GB15109) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |