Reactivity: | Human, Mouse |
Applications: | WB, ELISA |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Polyclonal antibody |
Gene Name: | protein phosphatase 2 regulatory subunit B'epsilon |
Gene Symbol: | PPP2R5E |
Synonyms: | B56E; B56epsilon; PP2A-B56δ/PR61δ/PPP2R5E |
Gene ID: | 5529 |
UniProt ID: | Q16537 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PP2A-B56δ/PR61δ/PPP2R5E (NP_006237.1). |
Dilution: | WB 1:500-1:2000 |
Purification Method: | Affinity purification |
Concentration: | 3.64 mg/ml |
Buffer: | Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |
Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Documents: | Manual-PPP2R5E antibody |
Background
The protein encoded by this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an epsilon isoform of the regulatory subunit B56 subfamily. Multiple transcript variants encoding several different isoforms have been found for this gene.
Images
![]() | Western blot analysis of various lysates using PP2A-B56δ/PR61δ/PPP2R5E Rabbit pAb (A15084) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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