| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Tyrosine-protein kinase JAK1 |
Synonyms: | JAK1A, JAK1B |
Immunogen: | KLH conjugated Synthetic phosphopeptide corresponding to Human JAK1(Tyr1034) |
Uniprot ID: | P23458 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 133 kDa / 130 kDa |
Product Usage Information
WB | Human | 1: 100-1: 300 | HeLa+pervanadate |
Background
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Directly phosphorylates STAT but also activates STAT signaling through the transactivation of other JAK kinases associated with signaling receptors.
Images
| WB analysis of Phospho-JAK1(Y1034) (GB115604). |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |