RIMS2 Rabbit pAb (20 μl)

RIMS2 Rabbit pAb (20 μl)

Brand: Abclonal
Cat. #: A14990
Availability: In Stock
$108.00
-+
Reactivity:   Human, Rat    
Applications:   WB, ELISA    
Host Species:   Rabbit    
Isotype:   IgG    
Clonality:   Polyclonal antibody    
Gene Name:   regulating synaptic membrane exocytosis 2
Gene Symbol:   RIMS2
Synonyms:   OBOE; RIM2; CRSDS; RAB3IP3; RIMS2
Gene ID:   9699
UniProt ID:   Q9UQ26
Immunogen:   Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human RIMS2 (NP_055492.3).
Dilution:   WB 1:500-1:2000
Purification Method:   Affinity purification
Concentration:   2.35 mg/ml
Buffer:   Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Storage:   Store at -20°C. Avoid freeze/thaw cycles.
Documents: Manual-RIMS2 antibody




Background

The protein encoded by this gene is a presynaptic protein that interacts with RAB3, a protein important for normal neurotransmitter release. The encoded protein can also bind several other synaptic proteins, including UNC-13 homolog B, ELKS/Rab6-interacting/CAST family member 1, and synaptotagmin 1. This protein is involved in synaptic membrane exocytosis. Polymorphisms in this gene have been associated with degenerative lumbar scoliosis.




Images

RIMS2 antibodyWestern blot analysis of various lysates using RIMS2 Rabbit pAb (A14990) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 15s.



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