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| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SRPX rabbit polyclonal |
Gene Name: | Sushi repeat-containing protein SRPX2 |
Synonyms: | BPP, CBPS, PMGX, RESDX, SRPUL, SRPX2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SRPX |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 53 kDa |
Observed MW. | 74 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1500 | liver, placenta |
Background
SRPX2 (sushi-repeat-containing protein, X-linked 2) is a secreted protein expressed in neurons of the human adult brain, including the rolandic area . Firstly described as sushi-repeat protein up-regulated in leukemia (SPRUL) in leukemia cells with dysregulated expression at the transcriptional level, SRPX2 has been recently shown as a multifunctional protein. SRPX2 is a ligand for uPAR, the urokinase-type plasminogen activator (uPA) receptor . It is involved in seizure disorders, angiogenesis and cellular adhesion . The involvement of SRPX2 in disorders of language cortex and cognition suggests it has an important role in the perisylvian region critical for language development
Images
 | Western blot analysis of SRPX (GB113423) at dilution of 1: 1500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |