Reactivity: | Human, Mouse, Rat |
Applications: | WB, ELISA |
Host Species: | Rabbit |
Clonality: | Polyclonal antibody |
Gene Name: | RELT TNF receptor |
Gene Symbol: | RELT |
Synonyms: | AI3C; TRLT; TNFRSF19L; RELT |
Gene ID: | 84957 |
UniProt ID: | Q969Z4 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-162 of human RELT (NP_116260.2). |
Dilution: | WB 1:200-1:2000 |
Purification Method: | Affinity purification |
Concentration: | 2.51 mg/ml |
Buffer: | Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |
Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Documents: | Manual-RELT antibody |
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.
Images
![]() | Western blot analysis of various lysates using RELT Rabbit pAb (A15540) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60S. |
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