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Anti-SUV3L1 Rabbit pAb (100 μl)
| Reactivity: | H,M & H & H |
| Applications: | WB & IHC/IF & ICC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SUV3L1 rabbit polyclonal |
Gene Name: | ATP-dependent RNA helicase SUPV3L1, mitochondrial |
Synonyms: | Suppressor of var1 3-like protein 1, SUV3-like protein 1, Supv3l1, Suv3l1 |
Immunogen: | Recombinant protein corresponding to Mouse SUV3L1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 87 kDa |
Observed MW. | 87 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse | 1: 1000-1: 1500 | testis |
IHC | Human | 1: 750-1: 1500 | colon |
Background
Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates
Images
| Western blot analysis of SUV3L1 (GB112778) at dilution of 1: 1500 Lane 1: PC-3 cell lysate Lane 2: Mouse testis tissue lysate |
 | Immunohistochemistry analysis of paraffin-embedded human colon using SUV3L1 (GB112778) at dilution of 1: 1500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |