Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | BRAF35 rabbit polyclonal |
Gene Name: | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related |
Synonyms: | SMARCE1-related protein, BRCA2-associated factor 35, HMG box-containing protein 20B, Structural DNA-binding protein BRAF35, Hmg20b, Braf35, Hmgx2, Smarce1r |
Immunogen: | Recombinant protein corresponding to Mouse BRAF35 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 36 kDa |
Observed MW. | 36 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 1000-1: 2000 | 293T, A375, Jurkat, A431, Raji |
Background
CoREST (corepressor of repressor element-1-silencing transcription factor) is a chromatin- modifying complex that was first identified as a regulator of neuronal gene expression, having a essential role in neuronal differentiation . The CoREST complex is recruited by REST (RE1-silencing transcription factor) that recognizes the 21-nucleotide RE-1 sequence in the promoter of more than 1,700 different target genes in human and mouse . HMGB20B is one component of the CoREST complex, which mediates chromatin remodeling and repression of specific genes involved in neuronal differentiation through modulation of chromatin structure.CoREST (corepressor of repressor element-1-silencing transcription factor) is a chromatin- modifying complex that was first identified as a regulator of neuronal gene expression, having a essential role in neuronal differentiation . The CoREST complex is recruited by REST (RE1-silencing transcription factor) that recognizes the 21-nucleotide RE-1 sequence in the promoter of more than 1,700 different target genes in human and mouse . HMGB20B is one component of the CoREST complex, which mediates chromatin remodeling and repression of specific genes involved in neuronal differentiation through modulation of chromatin structure.
Images
![]() | Western blot analysis of BRAF35 (GB112980) at dilution of 1: 2000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |