BRMS1 Rabbit mAb (20 μl)

BRMS1 Rabbit mAb (20 μl)

Brand: Abclonal
Cat. #: A0768
Availability: In Stock
$128.00
-+
Reactivity: Human, Mouse, Rat    
Applications: WB, IHC, ELISA    
Host Species: Rabbit    
Clonality: Monoclonal antibody    
Gene Name: BRMS1 transcriptional repressor and anoikis regulator
Gene Symbol: BRMS1
Synonyms: BRMS1; breast cancer metastasis-suppressor 1
Gene ID: 25855
UniProt ID: Q9HCU9
Clone ID: 5Y8J3
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BRMS1 (Q9HCU9).
Dilution: WB 1:500-1:1000; IHC 1:50-1:200
Purification Method: Affinity purification
Concentration: 1.20 mg/mL
Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Documents: Manual-BRMS1 antibody




Background

This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.




Images

BRMS1 antibodyWestern blot analysis of lysates from A549 cells, using BRMS1 Rabbit mAb (A0768) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 30s.
Immunohistochemistry analysis of paraffin-embedded Human esophageal using BRMS1 Rabbit mAb (A0768) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Bufferr (pH 6.0) prior to IHC staining.
Immunohistochemistry analysis of paraffin-embedded Mouse brain using BRMS1 Rabbit mAb (A0768) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Bufferr (pH 6.0) prior to IHC staining.
Immunohistochemistry analysis of paraffin-embedded Rat liver using BRMS1 Rabbit mAb (A0768) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Bufferr (pH 6.0) prior to IHC staining.



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