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Anti-Bcl 7A Rabbit pAb (100 μl)
| Reactivity: | H & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Bcl 7A rabbit polyclonal antibody |
Gene Name: | B-cell CLL/lymphoma 7 protein family member A |
Synonyms: | Bcl7a, BCL7, B cell CLL/lymphoma 7A, B cell CLL/lymphoma 7 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human Bcl 7A |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. | 23 kDa |
Observed MW. | 38 kDa |
Uniprot ID: | Q4VC05 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 250-1: 500 | 293T |
IHC/IF | Mouse, Rat | 1: 400-1: 800 | cerebellum, hippocampus, prefrontal lobe |
Background
This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.
Images
 | Western blot analysis of Bcl7a (GB112383) at dilution of 1: 250 |
 | Immunofluorescence of paraffin embedded mouse cerebellum using BC17a (GB112383) at dilution of 1: 400 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse prefrontal lobe using BC17a (GB112383) at dilution of 1: 400 (400x lens) |
 | Immunofluorescence of paraffin embedded rat cerebellum using BC17a (GB112383) at dilution of 1: 400 (400x lens) |
 | Immunofluorescence of paraffin embedded rat hippocampus using BC17a (GB112383) at dilution of 1: 400 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |