| Reactivity: | M,R & R | 
| Applications: | WB & IHC/IF | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Full Name: | CCRL2 rabbit polyclonal antibody | 
| Gene Name: | C-C chemokine receptor-like 2 | 
| Synonyms: | Chemokine receptor CCR11, G-protein coupled beta chemokine receptor, Lipopolysaccharide-inducible C-C chemokine receptor, L-CCR, Ccrl2, Ccr11, Lccr | 
| Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CCRL2 | 
| Isotype: | IgG | 
| Purity: | Affinity purification | 
| Subcellular location: | Cell membrane | 
| Uniprot ID: | O00421 | 
Product Usage Information
| Applications | Species | Dilution | Positive Sample | 
| IHC/IF | Human, Mouse, Rat | 1: 150-1: 300 | brain, placenta, spleen | 
Background
Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in modulating chemokine-triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand to CMKLR1, a functional signaling receptors. Plays a critical role for the development of Th2 responses.
Images
| Immunohistochemistry of paraffin embedded human placenta using CCRL2 (GB112260) at dilution of 1:300 (400x lens) | |
| 
 | Immunohistochemistry of paraffin embedded mouse spleen using CCRL2 (GB112260) at dilution of 1:300 (400x lens) | 
| 
 | Immunohistochemistry of paraffin embedded rat brain using CCRL2 (GB112260) at dilution of 1:300 (400x lens) | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |