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Anti-CD8 alpha Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CD8 alpha rabbit polyclonal antibody |
Gene Name: | T-cell surface glycoprotein CD8 alpha chain |
Synonyms: | CD8A, CD8, Leu2, MAL, p32,CD8a molecule, CD8 alpha |
Immunogen: | Recombinant protein corresponding to Human CD8a |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | P01732 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1:500-1:1000 | colon cancer, ovarian cancer, liver cancer, colon, tonsil |
Background
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain.
Images
| Immunohistochemistry analysis of paraffin embedded human colon cancer using CD8A (GB114123) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded human ovarian cancer using CD8A (GB114123) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded human liver cancer using CD8A (GB114123) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded human colon using CD8A (GB114123) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded human tonsil using CD8A (GB114123) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |