| Reactivity: | M,R & M,R | 
| Applications: | WB & IHC/IF | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Gene Name: | Muscarinic acetylcholine receptor M1  | 
Synonyms:  | Chrm-1, Chrm1  | 
Immunogen:  | KLH conjugated Synthetic peptide corresponding to Mouse Muscarinic Acetylcholine Receptor 1/CHRM1  | 
Uniprot ID:  | P12657  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Subcellular location:  | Cell membrane, Cell junction  | 
Predicted MW. / Observed MW.  | 51 kDa / 51 kDa  | 
Product Usage Information
WB  | Mouse, Rat  | 1: 300-1: 500  | brain, prostate  | 
IHC/IF  | Mouse, Rat  | 1: 500-1: 1000  | brain, cerebellum  | 
Background
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Images
  | Western blot analysis of CHRM1 (GB114288) at dilution of 1: 500  | 
  | Immunohistochemistry analysis of paraffin embedded mouse Brain using CHRM1 (GB114288) at dilution of 1: 500  | 
  | Immunohistochemistry analysis of paraffin embedded rat cerebellum using CHRM1 (GB114288) at dilution of 1: 500  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |