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Anti-COLEC11 Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R & M,R |
| Applications: | WB & IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Collectin-11 |
Synonyms: | CL K1, CL K1 I, CL K1 II, CL K1 IIa, CL K1 IIb, CLK1, Collectin 11, Collectin kidney protein 1, collectin sub family member 11 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse COLEC11 |
Uniprot ID: | Q3SXB8 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 29 kDa / 35 kDa |
Product Usage Information
WB | Mouse | 1: 2000-1: 3000 | liver |
Background
Lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding.
Images
| Western blot analysis of COLEC11 (GB115040) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |