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Anti-Ca(v)3.3 Rabbit pAb (100 μl)
| Reactivity: | R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Ca(v)3.3 rabbit polyclonal |
Gene Name: | calcium voltage-gated channel subunit alpha1 I |
Synonyms: | Cacna1i |
Uniprot ID: | |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CACNA1I |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 243 kDa |
Observed MW. | 250 kDa |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Rat | 1: 300-1: 600 | brain |
Background
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle.
Images
 | Western blot analysis of Ca(v)3.3 (GB113006) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
