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Anti-Cardiac Troponin C Rabbit pAb (100 μl)
| Reactivity: | R |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Cardiac Troponin C rabbit polyclonal |
Gene Name: | Troponin C, slow skeletal and cardiac muscles |
Synonyms: | TN-C, Tnnc1, Tncc, CMD1Z, troponin C type 1 (slow), Cardiac troponin C, CMH13 |
Immunogen: | Recombinant protein corresponding to Human Cardiac Troponin C |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoskeleton, Cytoplasm |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Rat | 1: 1000-1: 2000 | skeletal muscle |
Background
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. TnC plays an important role in excitation-contraction coupling and is the primary target of compounds such as levosimendan that augment Ca2+ responsiveness of the thin filament.
Images
 | Immunohistochemistry analysis of paraffin-embedded rat skeletal muscle using Cardiac (GB112706) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |