| Reactivity: | M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Cathepsin Z |
Synonyms: | Ctsz, Cathepsin B2, Cathepsin IV, Cathepsin P, Preprocathepsin P, Carboxypeptidase LB, CTSX |
Immunogen: | Recombinant protein corresponding to Mouse Cathepsin Z |
Uniprot ID: | Q9WUU7 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Lysosome |
Predicted MW. / Observed MW. | 34 kDa / 37 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | lung, spleen, lymph node |
IHC/IF | Mouse, Rat | 1: 600-1: 1200 | liver, rectum |
Background
The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis.
Images
| Western blot analysis of Cathepsin Z (GB112171) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse liver using Cathepsin-Z (GB112171) at dilution of 1: 600 |
| Immunofluorescence analysis of paraffin embedded mouse rectum using Cathepsin-Z (GB112171) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |