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Anti-Cyclin E1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | G1/S-specific cyclin-E1 |
Synonyms: | CCNE1, CCNE, pcyclin E1, Cyclin E1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human Cyclin E1 |
Uniprot ID: | P24864 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 47 kDa / 47 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 900 | testis, colon, placenta |
Background
Cyclin E1 (CCNE1) is a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. CCNE1, an essential cyclin activating Cdk2, regulates the G1-S phase transition of the mammalian cell division cycle. Its timing expression plays a direct role in the initiation of DNA replication , the control of histone biosynthesis, and the centrosome cycle. CCNE1 is associated with disease progression in various malignancies and is associated clinically with poor prognosis.
Images
| Western blot analysis of Cyclin E1 (GB111938) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |