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| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Dicer rabbit polyclonal antibody |
Gene Name: | Endoribonuclease Dicer |
Synonyms: | DICER1, DCR1, Dicer, Dicer1e, HERNA, MNG1, RMSE2, K12H4.8-LIKE, dicer 1, ribonuclease III |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Dicer |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Uniprot ID: | Q9UPY3, Q8R418 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 1000-1: 2000 | colon, kidney, lung, pancreas, small intestine, uterus |
Background
Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation.
Images
 | Immunohistochemistry of paraffin embedded human colon using Dicer (GB11410) at dilution of 1:1000 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse kidney using Dicer (GB11410) at dilution of 1:1000 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse pancreas using Dicer (GB11410) at dilution of 1:1000 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse uterus using Dicer (GB11410) at dilution of 1:1000 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat kidney using Dicer (GB11410) at dilution of 1:1000 (400x lens) |
 | Immunofluorescence of paraffin embedded human lung using Dicer (GB11410) at dilution of 1:1000 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse colon using Dicer (GB11410) at dilution of 1:1000 (400x lens) |
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Immunofluorescence of paraffin embedded mouse lung using Dicer (GB11410) at dilution of 1:1000 (400x lens) |
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Immunofluorescence of paraffin embedded rat small intestine using Dicer (GB11410) at dilution of 1:1000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |