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Anti-Dynein axonemal intermediate chain Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Cytoplasmic dynein 1 intermediate chain 1 |
Synonyms: | DH IC 1, DNCI1, DNCIC1, DYNC1I1 |
Immunogen: | Recombinant protein corresponding to Mouse Dynein axonemal intermediate chain |
Uniprot ID: | O88485 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 71 kDa / 85 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 300-1: 800 | brain |
Background
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
Images
| Western blot analysis of DYNC1I1 (GB114246) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |