| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | EARP and GARP complex-interacting protein 1 |
Synonyms: | EIPR-1, TSSC1 |
Immunogen: | Recombinant protein corresponding to Mouse EIPR1 |
Uniprot ID: | Q8K0G5 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Golgi apparatus |
Product Usage Information
IHC/IF | Human | 1: 800-1: 1600 | liver cancer, lung cancer |
Background
Acts as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network (By similarity). Mediates the recruitment of Golgi-associated retrograde protein (GARP) complex to the trans-Golgi network and controls early endosome-to-Golgi transport of internalized protein (By similarity). Promotes the recycling of internalized transferrin receptor (TFRC) to the plasma membrane through interaction with endosome-associated recycling protein (EARP) complex (By similarity). Controls proper insulin distribution and secretion, and retention of cargo in mature dense core vesicles (By similarity).
Images
| Immunohistochemistry analysis of paraffin embedded human liver cancer using EIPR1 (GB114481) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded human lung cancer using EIPR1 (GB114481) at dilution of 1: 800 |
| Immunofluorescence analysis of paraffin embedded human liver cancer using EIPR1 (GB114481) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |