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| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Armenian Hamster |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | FITC. Ex:491nm. Em:516nm. |
| Gene Name: | CD3 antigen, epsilon polypeptide |
| Gene Symbol: | Cd3e |
| Synonyms: | CD3; T3e; CD3epsilon |
| Gene ID: | 12501 |
| Immunogen: | Recombinant protein of Mouse CD3e. |
| Dilution: | FC,The suggested use of this reagent is ≤0.5 µg per 10^6 cells in 100 µl volume. |
| Purification Method: | Affinity purification |
| Concentration: | 0.5 mg/mL |
| Buffer: | 10 mM NaH₂PO₄, 150 mM NaCl, 0.09% NaN₃,0.1% gelatin, pH7.2 |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Cd3e Antibody |
Background
Predicted to enable several functions, including SH3 domain binding activity; identical protein binding activity; and protein heterodimerization activity. Involved in nervous system development and positive regulation of cell adhesion. Acts upstream of or within several processes, including positive regulation of T cell activation; positive regulation of cytokine production; and regulation of signal transduction. Located in several cellular components, including dendritic spine; external side of plasma membrane; and immunological synapse. Part of alpha-beta T cell receptor complex. Is expressed in colon and hemolymphoid system. Human ortholog(s) of this gene implicated in immunodeficiency 18. Orthologous to human CD3E (CD3e molecule).
Images
 | Flow cytometry: 1×10^6 C57BL/6 mouse splenocytes were surface-stained with FITC Armenian Hamster IgG isotype control (5 μl/Test,left) or FITC Anti-Mouse CD3e mAb (A23322,2 μg/mL,right). |
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