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FITC Anti-CD73 Rabbit pAb (100 μl)
| Reactivity: | H, M, R |
| Applications: | FC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | 5'-nucleotidase |
Synonyms: | 5 NT, 5 nucleotidase, 5' nucleotidase, ecto (CD73), CD73, E5NT, Ecto 5 nucleotidase, eN, eNT, NT, NT5, NT5E, |
Immunogen: | Recombinant protein corresponding to Mouse CD73 |
Uniprot ID: | Q61503 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Product Usage Information
FC | Human, Mouse, Rat | 1: 100-1: 200 | R-MSC, 4T1 |
Background
Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment.Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection.Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases.Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion.
Images
| Flow cytometric analysis of CD73. Sample: R-MSC. Antibody: FITC conjugated Anti-CD73 Rabbit pAb(ZB115637-FITC red histogram), 1: 100, RT 30 min. Control Antibody: FITC conjugated Goat Anti-Rabbit lgG (GB22303, open histogram), 1: 200, RT 30 min. |
| Flow cytometric analysis of CD73. Sample: 4T1. Antibody: FITC conjugated Anti-CD73 Rabbit pAb(ZB115637-FITC red histogram), 1: 100, RT 30 min. Control Antibody: FITC conjugated Goat Anti-Rabbit lgG (GB22303, open histogram), 1: 200, RT 30 min. |
| Flow cytometric analysis of CD73. Sample: Daudi. Antibody: FITC conjugated Anti-CD73 Rabbit pAb(ZB115637-FITC red histogram), 1: 100, RT 30 min. Control Antibody: FITC conjugated Goat Anti-Rabbit lgG (GB22303, open histogram), 1: 200, RT 30 min. |
| Flow cytometric analysis of CD73. Sample: Raw264.7. Antibody: FITC conjugated Anti-CD73 Rabbit pAb(ZB115637-FITC red histogram), 1: 100, RT 30 min. Control Antibody: FITC conjugated Goat Anti-Rabbit lgG (GB22303, open histogram), 1: 200, RT 30 min. |
| Flow cytometric analysis of CD73. Sample: U-87 MG. Antibody: FITC conjugated Anti-CD73 Rabbit pAb(ZB115637-FITC red histogram), 1: 100, RT 30 min. Control Antibody: FITC conjugated Goat Anti-Rabbit lgG (GB22303, open histogram), 1: 200, RT 30 min. |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |