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| Reactivity: | Human |
| Applications: | WB, ELISA |
| Host Species: | Rabbit |
| Clonality: | Polyclonal antibody |
| Gene Name: | FLVCR choline and heme transporter 1 |
| Gene Symbol: | FLVCR1 |
| Synonyms: | PCA; AXPC1; FLVCR; PCARP; MFSD7B; SLC49A1; FLVCR1 |
| Gene ID: | 28982 |
| UniProt ID: | Q9Y5Y0 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human FLVCR1 (NP_054772.1). |
| Dilution: | WB 1:500-1:2000 |
| Purification Method: | Affinity purification |
| Concentration: | 1.01 mg/mL |
| Buffer: | Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-FLVCR1 antibody |
Background
This gene encodes a member of the major facilitator superfamily of transporter proteins. The encoded protein is a heme transporter that may play a critical role in erythropoiesis by protecting developing erythroid cells from heme toxicity. This gene may play a role in posterior column ataxia with retinitis pigmentosa and the hematological disorder Diamond-Blackfan syndrome.
Images
 | Western blot analysis of lysates from Raji cells, using FLVCR1 Rabbit pAb (A15153) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 60s. |
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