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Anti-Filaggrin Rabbit pAb (100 μl)
| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Filaggrin rabbit polyclonal antibody |
Gene Name: | Filaggrin |
Synonyms: | Flg, ATOD2, Epidermal filaggrin, Profilaggrin, Filaggrin precursor |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Filaggrin |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 36 kDa |
Observed MW. | 44 kDa |
Uniprot ID: | P11088 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse | 1: 250-1: 500 | skin |
Background
The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules.
Images
| Western blot analysis of Filaggrin (GB112010) at dilution of 1: 250 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |