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ABflo® 450 Rabbit anti-Human β2 Microglobulin mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 450. Ex:406nm. Em:445nm. |
| Gene Name: | beta-2-microglobulin |
| Gene Symbol: | B2M |
| Synonyms: | IMD43; AMYLD6; MHC1D4 |
| Gene ID: | 567 |
| UniProt ID: | P61769 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-119 of human β2 Microglobulin (NP_004039.1). |
| Dilution: | FC, 5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-B2M Antibody |
Background
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
Images
 | Flow cytometry: 1×10^6 Daudi cells (negative control,left) and HeLa cells (right) were surface-stained with ABflo® 450 Rabbit anti-Human β2 Microglobulin mAb (A26843,5 μl/Test,orange line) or ABflo® 450 Rabbit IgG isotype control (5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 HeLa cells were surface-stained with ABflo® 450 Rabbit IgG isotype control (5 μl/Test,left) or ABflo® 450 Rabbit anti-Human β2 Microglobulin mAb (A26843,5 μl/Test,right). |
 | Flow cytometry: 1×10^6 Human PBMC were surface-stained with ABflo® 450 Rabbit anti-Human β2 Microglobulin mAb (A26843,5 μl/Test,orange line) or ABflo® 450 Rabbit IgG isotype control (5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).Cells in the Lymphocytes gate were used for analysis. |
 | Flow cytometry: 1×10^6 Human PBMC were surface-stained with ABflo® 450 Rabbit IgG isotype control (5 μl/Test,left) or ABflo® 450 Rabbit anti-Human β2 Microglobulin mAb (A26843,5 μl/Test,right).Cells in the Lymphocytes gate were used for analysis. |
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